6. Do DIDP and DINP pose risks to human health? GreenFacts
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:68515-48-0 Other Names:Diisononyl phthalate
- MF:C26H42O4 Diisononyl Phthalate
- EINECS No.:249-079-5
- Purity:99.5%Min
- Type:New Type Environment DINP Plasticizer
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
- MOQ:200kgs
- Package:200kgs/battle
- Function:PVC Plasticizer
DINP. Repeated dose toxicity (RDT) and reproductive effects are considered to be the critical endpoints in the risk assessment of DINP.. Risk characterisation . Workers For the dermal
The assessment found that current exposure to these phthalates from food is not of concern for public health. For DBP, BBP, DEHP, and DINP, exposure was found to range
EPA Releases Draft Risk Evaluation Documents for Two
- Classification:Chemical Auxiliary Agent
- CAS No.:28553-12-0
- Other Names:Di-isononyl phthalate
- MF:C26H42O4
- EINECS No.:271-090-9
- Purity:99%, 99%
- Type:DINP
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ:1000KG
- Package:25kg/drum
- Certification:ISO9001
DINP . Although DIDP and DINP have similar uses, EPA identified several important differences in the potential effects on human health posed by DIDP and DINP. Both
risk assessment report on DINP in 2003 (ECB, 2003) concluding that DINP poses no risk to either human health or the environment. The risk assessment report clearly states there is no need
Risk Evaluation for Di-isodecyl phthalate (DIDP) (1,2-Benzene
- Classification:Chemical Auxiliary Agent
- CAS No.:28553-12-0
- Other Names:Diisononyl phthalate
- MF:C26H42O4
- EINECS No.:271-090-9
- Purity:99.0%, 99.5%
- Type:Flocculant, Flocculant
- Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
- MOQ:200kgs
- Package:200kgs/battle
- Certification:ISO9001
EPA also preliminarily determined that DIDP does not pose unreasonable risk of injury to human health for consumers or the general population or pose unreasonable risk to
uncertainties in the exposure and health effects database for DINP and DIDP. EUROPEAN CHEMICALS AGENCY (2013) “no risk is expected from combined exposure to DINP and
Phthalates and Their Impacts on Human Health PMC
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:28553-12-0
- Other Names:Diisononyl phthalate
- MF:C26H42O4 Diisononyl Phthalate
- EINECS No.:271-090-9
- Purity:99.0%, 99.5%
- Type:Flocculant, Flocculant
- Usage:Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ:1000KG
- Package:25kg/drum
- Storage:Dry Place
DiNP and DEHP are banned in toys; DEHP is banned in food-handling gloves: Europe [42,43] DEHP, DBP, DiBP, and BBP are banned in all PVC and plasticized toys and childcare articles;
DINP. Repeated dose toxicity (RDT) and reproductive effects are considered to be the critical endpoints in the risk assessment of DINP.. Risk characterisation . Workers For the dermal
Human Biological Monitoring of Diisononyl Phthalate
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:28553-12-0 Other Names:Diisononyl phthalate
- MF:C26H42O4 Diisononyl Phthalate
- EINECS No.:271-090-9
- Purity:99.5%, 99.5%
- Type:Flocculant, Flocculant
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Textile Auxiliary Agents, Water Treatment Chemicals
- MOQ:200kgs
- Package:200kgs/battle
- Storage:Dry Place
It is desirable to measure more than one secondary metabolite of DINP/DIDP in human biological monitoring studies to assess human exposure. However, due to logistic and economic
DIDP. Effects assessment. Toxicokinetics, metabolism and distribution. The data available on toxicokinetic suggest that, via gastro-intestinal tract (GIT), absorption of DIDP decreases as dose increases (56% at the low dose of 0.1 mg/kg, 46% at the mid dose of 11.2 mg/kg and 17% at the high dose of 1,000 mg/kg) and seems to be of saturable mechanism; when dose increases, an
- What are the critical health effects of DIDP & DINP?
- Harmful effects to the liver and reproductive effects due to repeated exposure are considered to be the critical health effects in the risk assessment of DIDP and DINP. Risks are assessed by comparing worst case exposures to the exposures at which no harmful effects were observed in animal studies.
- Are DINP/DIDP exposures a concern for workers?
- It is concluded that exposures to DINP or DIDP are of no concern for workers because they are well below the amounts that would cause harmful effects. The assessment concluded that there is at present no need for further information and/or testing or for further risk reduction measures beyond those being applied already. More...
- How safe is DIDP & DINP?
- The environmental exposure assessment of DIDP and DINP has shown that the exposure of adults and infants via the environment is within the margins of safety when considering liver toxicity and developmental effects.
- Does DIDP pose an unreasonable risk to human health?
- EPA preliminarily determined that DIDP poses unreasonable risk of injury to human health to workers exposed to the chemical. EPA also preliminarily determined that DIDP does not pose unreasonable risk of injury to human health for consumers or the general population or pose unreasonable risk to the environment.
- Are DIDP and DINP TSCA safe?
- There are other uses of DIDP and DINP that are generally excluded from TSCA, such as personal care products, cosmetics, and food contact materials, and EPA did not evaluate risk associated with these uses. The risk evaluations of DIDP and DINP are the first two manufacturer-requested risk evaluations EPA has conducted.
- Can DIDP cause cancer?
- For DIDP, EPA determined that the evidence is not strong enough to conclude that it can cause cancer in people. By contrast, EPA determined that DINP could cause cancer at higher levels of exposure than those that cause liver damage and developmental toxicity.