factory supply Topical Polymeric Films: Plasticizers

  • factory supply Topical Polymeric Films: Plasticizers
  • factory supply Topical Polymeric Films: Plasticizers
  • factory supply Topical Polymeric Films: Plasticizers
  • Are polymeric drug delivery systems plasticizers?
  • Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
  • What is a topical film forming system?
  • Topical film forming systems are such developing drug delivery systems meant for topical application to the skin, which adhere to the body, forming a thin transparent film and provide delivery of the active ingredients to the body tissue.
  • Are film forming systems a promising choice for topical and transdermal drug delivery?
  • The transparency is an appreciable feature of this polymeric system which greatly influences the patient acceptance. In the current discussion, the film forming systems are described as a promising choice for topical and transdermal drug delivery.
  • Is hydrophilic polymer an internal plasticizer of polymeric drug delivery systems?
  • As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems. In case of contact with body fluids after application the hydrophilic plasticizer can be released from polymer and thus conditions for the incorporated drug release are changed.
  • Which plasticizer should be used in film forming system?
  • The plasticizer used should be compatible with the polymers used and should have low skin permeability. Commonly used plasticizers are glycerine, polyethylene glycol, sorbitol, dibutyl phthalate, propylene glycol, triethyl citrate etc. . 8. Evaluation of film forming system 8.1. Film formation
  • Which polymers are used in drug delivery systems?
  • Aliphatic polyesters are the most frequently used polymers in drug delivery systems. Star-like copolymers of hydroxy acids with polyhydric alcohols such as dipentaerythritol are particularly interesting. They possess good mechanical properties, however the brittleness is their major drawback for many applications.

Recommended hot-selling products