Non-Phthalate Plasticizer Performs Comparably in Blood Bag Study

  • Non-Phthalate Plasticizer Performs Comparably in Blood Bag Study
  • Non-Phthalate Plasticizer Performs Comparably in Blood Bag Study
  • Non-Phthalate Plasticizer Performs Comparably in Blood Bag Study
  • Do PVC blood bags plasticized with DEHT provide adequate red blood cell quality?
  • As a future aspect, the individual contribution of different pro-duction parameters should be further explored. In conclusion, this study demonstrates that PVC blood bags plasticized with DEHT provide adequate red blood cell quality during 49 days of storage.
  • Are PVC-DEHT blood bags phthalate?
  • PVC-DEHT bags hold as high physical and functional quality as bags plasticized with DEHP. Therefore, we consider PVC-DEHT blood bags a recommendable non-phthalate candidate for future blood component collection and storage. Walter CW: Invention and develop-ment of the blood bag. Vox Sang 1984; 47:318 24
  • Can plasticizers replace DEHP in blood bags?
  • Several plasticizers have been suggested as substitutes to DEHP in blood bags. Di(2-ethylhexyl) terephthalate (DEHT) and di-isononyl cyclohexane-1,2-dicarboxylic acid (DINCH) have shown the greatest potential so far, despite providing inferior RBC quality in previous studies [9 13].
  • Is DEHT a good replacement for DEHP in blood bags?
  • Vox Sanguinis published by John Wiley & Sons Ltd on behalf of International Society of Blood Transfusion. Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags.
  • Does plasticizer exposure affect platelet quality?
  • There were no significant differences between the properties of platelets produced in DEHT or DEHP systems (Table 3). The collective assessment of the platelet parameters demonstrated an overall high quality, independent of plasticizer exposure. No alterations in MPV were observed.
  • Are commercial blood bags made of polyvinyl chloride (PVC)?
  • All other authors declare no conflicts of interest. Material and financial support was received by Macopharma. Background and objectives Commercial blood bags are predominantly made of polyvinyl chloride (PVC) plasticized with di (2-ethylhexyl) phthalate (DEHP).

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