What is the best alternative to DEHP for medical
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Toxicology. All of the toxicology data available for PVC plasticizers is based on rodent toxicology. In a comprehensive European 1 study, DEHP is reported to have a NOAEL (no observable adverse effect level) of 4.8
The plasticizers used to render PVC flexible constitute about a third of the vinyl compound by weight and have a significant effect on overall properties and performance. The most widely used plasticizer in medical applications, DEHP
A Comparison of Plasticizers for Use in Flexible Vinyl Medical
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Apr 1, 2001Table I. Performance of plasticizers compounded to a standard modulus (0.5-mm film). Study 2 took a different approach, holding the amount of plasticizer in the compound
All plasticizers have trade-offs. Look beyond cost, and consider factors like toxicology, sterilization, efficiency, compatibility, migration and crazing, water blushing, and the impact to your process. Start with a proper scientific
Health, Eco Concerns Give Non-Phthalate
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BASF’s Napiany notes that while plasticizers like DOTP and DINCH are fairly comparable to DEHP, compounders must keep in mind that plasticizers are always a little different from each other. For example, slight
DOTP plasticizer producers specify a DEHP content of less than 50ppm, but almost all shipments contain significantly less than that. In contrast, TOTM can contain as much as 2,000ppm of DEHP and is never free of it. This
The Long Goodbye to DEHP-plasticized PVC
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The idea of scrapping the use of polyvinylchloride (PVC) materials containing di(2-ethylhexyl)phthalate (DEHP) plasticizers is not new. However, despite such endeavors, both PVC and DEHP plasticizer still abound in a
The comparison of new plasticizers with DEHP revealed their slightly higher T g and the mechanical properties of the PVC blend were much better than those in case of DEHP. A good performance of these plasticizers should be
Henan Chemger-Premium Chemical Raw Material Supplier
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- Other Names:Plasticizer
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- Type:Plastizer
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- MOQ:200kgs
- Package:200kgs/battle
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Quality, service and reputation are the basis and guarantee for us to win the market and customers. The main products are pvc resin powder, titanium dioxide, iron oxide,
(Figure 1.) Phthalate plasticizers are colorless liquids like vegetable oil with a faint odor, and they are insoluble in water. They are however, miscible in mineral oil, hexane, and most organic solvents. This makes them readily soluble in bodily
- Are alternative plasticizers safe for flexible PVC medical compounds?
- While phthalate esters such as DEHP are the most widely used plasticizers for flexible PVC medical compounds and have been for 50 years, issues concerning their possible effects on human health have caused some device manufacturers to consider compounds containing alternative plasticizers. Sometimes the pressure to do so is considerable.
- What are the advantages of Eastman's DOTP plasticizers?
- Eastman sees its DOTP plasticizers as offering an easy replacement for DEHP and TOTM. Advantages cited include: • Dry time fairly similar to that of DINP, and better than Hexamoll DINCH. • Efficiency fairly similar to DINP and DINCH, while slightly lower than DEHP.
- Are there alternative plasticizers?
- “There are a number of alternative plasticizers on the market. While Teknor Apex is best known as a manufacturer of medical-grade PVC compounds, we also produce some of these plasticizers,” notes Galland.
- What is the best non-Phthalate plasticizer for PVC?
- DOTP from Eastman has been available for several decades as Eastman 168, and the company claims it is the market-leading non-phthalate plasticizer for PVC, offering performance equal to or better than most non-phthalates. It offers good performance properties, optimal low-temperature flexibility, and non-migration properties.
- Are PVC plasticizers toxic?
- Toxicology. All of the toxicology data available for PVC plasticizers is based on rodent toxicology. In a comprehensive European1 study, DEHP is reported to have a NOAEL (no observable adverse effect level) of 4.8 milligrams per kilogram of body weight, while TOTM has a NOAEL of 100 milligrams (see table).
- How safe is DOTP compared to DEHP?
- By comparison, DOTP is listed at 500-700 milligrams, making it 100 to 140 times safer than DEHP for rodents and five to seven times safer than TOTM. The same study listed NOAELs for ATBC (acetyl tributyl citrate), DINCH (di-isononyl cyclohexanoate), and DOA (di-octyl adipate) plasticizers at 100, 107, and 200, respectively.
