The Facts about DEHP/DOP nigeria

  • The Facts about DEHP/DOP nigeria
  • The Facts about DEHP/DOP nigeria
  • The Facts about DEHP/DOP nigeria
  • Who is most exposed to DEHP?
  • Exposure to DEHP apparently occurs during the entire human life time, from different sources. Exposure may therefore be equated with persistent low dose exposure. New-borns are probably the most sensitive sub-population, exposed via many sources, and perhaps at higher levels than the adults.
  • How many tons of DEHP are produced per year?
  • DEHP is produced at more than 2 million tons annually worldwide . DEHP consists of a pair of eight-carbon esters linked to a benzene-dicarboxylic acid ring with a molecular weight (MW) equal to 390.56 g-mol −1 and a chemical formula of C 24 H 38 O 4.
  • Which metabolites are metabolized by DEHP?
  • When DEHP enters the body, it is metabolized into different metabolites. The primary monoester metabolites of DEHP are di-n-octyl phthalate (DnOP), di-n-butyl phthalate (DnBP), benzyl butyl phthalate (BBzP), and diethyl phthalate (DEP) .
  • Why does DEHP form more octanol in water?
  • The probable explanation is that DEHP readily forms more or less colloidal dispersions in water. Natural constituents in water may influence the solubility. A non-colloidal solubility of 0.003 mg/L is chosen for the Risk assessment. The Henry´s law constant for DEHP is 4.43 Pa m 3 /mol. The octanol-water partition coefficient, log Kow, is 7.5.
  • Is MPAE a metabolite of DEHP?
  • Through the urinary mPAE concentrations, it was reported that the exposure of older adults to DEHP was more profound than with young adults (Zhang et al., 2020). Also, the DEHP metabolites detected in blood samples were predominantly mEHP, ascribed to its low water solubility (Koch et al., 2004).
  • Is DEHP soluble in water?
  • "Bis- (2-Ethylhexyl) Phthalate, DEHP), Summary Risk Assessment report" , 2008. p.3-4. The same information on DEHP is a colourless oily liquid that is soluble in fat and not very soluble in water. It is not very volatile so does not vaporise readily into the atmosphere.

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