The Estrogenic Effects of Phthalates (DEHP DBP) in MCF-7 Cell

Impact of low concentrations of phthalates on the effects of

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Dibutyl Phthalate (DBP)
MF:C16H2204
EINECS No.:201-557-4
Purity:99%min
Type:Plastics Additives
Usage: Paper Chemicals,Coating Auxiliary Agents,
MOQ:200kgs
Package:200kgs/battle
Sample:Availabe

The present study demonstrates that even at a very low concentration, BBP, DBP, and DEHP were not only still capable of displaying estrogenic activity, but also of inducing an

They used embryonic leydig cell and MCF-7 cell and 10 μM of MEHP showed the estrogenic effect depending on the One study confirmed the decrease of natural estrogenic

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Comparison of In Vitro Endocrine Activity of Phthalates

Classification:Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Dibutyl phthalate DBP
MF:C16H22O4
EINECS No.:201-557-4
Purity:≥99.5
Type:PVC additives
Usage:Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:25kg/bag
Package:200kg/drum
Sample:Availabe

In the E-Screen assay, only DEHP moderately induced MCF-7 cell proliferation; none of the other tested substances were estrogenic or antiestrogenic. No androgenic or

Environmental estrogens represent a class of compounds that can mimic the function or activity of the endogenous estrogen 17 -estradiol (E2). Phthalates including butyl benzyl phthalate

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Estimation of estrogenic and anti-estrogenic activities of

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Dibutyl phthalate DBP
MF:C16H2204
EINECS No.:201-557-4
Purity:98%
Type:PVC additives
Usage:Leather Auxiliary Agents, PVC particles
MOQ:200kgs
Package:200kgs/battle
Sample:Availabe
Application:Plasticizer
Delivery:Within 7-15 Days

Phthalates are man-made chemicals abundantly found in the environment. Estrogenic activities of phthalate di and monoesters were studied by in vitro assay of human breast cancer MCF-7

Objective: To explore the effect and pathway of phthalates on the growth of MCF-7 breast cancer cells. Methods: MCF-7 cells were treated with benzyl butyl phthalate (BBP), di-n-butyl

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PHTHALATES INHIBIT TAMOXIFEN-INDUCED APOPTOSIS

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Dibutyl Phthalate (DBP)
MF:C16H2204
EINECS No.:201-557-4
Purity:99.5%, 99.5%min
Type:Plastics Additives
Usage:Plasticizer
MOQ:200kgs
Package:200kgs/battle
Application:Plasticizer

In order to further evaluate the potential role of the phthalates as environmental estrogens, the effect of phthalates was investigated on TAM-induced apoptosis in MCF-7

It is suggested that DEHP and DBP are estrogenic, and DEHP was stronger than DBP in the concentration of maximal efficacy in the MCF-7 cell proliferation. To evaluate the estrogenic

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Differential toxicological endpoints of di(2-ethylhexyl)

Classification:Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:DBP
MF:C16H2204
EINECS No.:201-557-4
Purity:99.8
Type:Adsorbent
Usage: Leather Auxiliary Agents, Rubber Auxiliary Agents
MOQ:25kg/bag
Package:200kg/drum
Application:Plasticizer

DAS et al.: DEHP EXPOSURE IN MCF-7 & MDA-MB-231 CELL LINES 1053 cancer cells5,9,17.Therefore, to evaluate the chemical’s proliferating potential, effects of DEHP and TAM have been studied

Although phthalates induced an increase in MCF-7 cell proliferation by an estrogenic effect, they could not induce CaBP-9k expression in the in vivo system, suggesting that the assays of estrogenic effects of various phthalates conducted in vitro and in vivo expression of CaBP-9k may produce conflicting results.

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