Benomyl, Aldehyde Dehydrogenase, DOPAL, and the
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:Dioctyl Phthalate
- MF:C6H4(COOC8H17)2
- EINECS No.:201-557-4
- Purity:99.5%, 99.5%
- Type:Liquid, plasticizer
- Usage:Coating Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Model:Dop Oil For Pvc
- Storage:Dry Place
ABSTRACT: The dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) is detoxified mainly by aldehyde dehydrogenase (ALDH). We find that the fungicide benomyl potently and
The dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) is detoxified mainly by aldehyde dehydrogenase (ALDH). We find that the fungicide benomyl potently and
Aldehyde dehydrogenase inhibition as a pathogenic
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:DiOctyle Phthalate DOP
- MF:C6H4(COOC8H17)2
- EINECS No.:201-557-4
- Purity:99 %
- Type:Adsorbent, Carbon Black
- Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ:200kgs
- Package:200kgs/battle
- Shape:Powder
- Place of Origin::China
- Item:T/T,L/C
To test if accumulation of ALDH substrates (i.e., DOPAL) caused benomyl’s neurotoxicity, DOPAL formation was inhibited with the MAO inhibitor pargyline. TH + neuronal loss was attenuated
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Benomyl, Aldehyde Dehydrogenase, DOPAL, and the
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:DiOctyle Phthalate DOP
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:≥99.5%
- Type:DOP
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ::10 Tons
- Package:25kg/drum
- Place of Origin::China
The dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) is detoxified mainly by aldehyde dehydrogenase (ALDH). We find that the fungicide benomyl potently and rapidly
This study lends support to the “catecholaldehyde hypothesis” that the autotoxic dopamine metabolite DOPAL plays a pathogenic role in PD. The dopamine metabolite 3,4
Benomyl, aldehyde dehydrogenase, DOPAL, and the
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:DOP Bis(2-ethylhexyl) phthalate
- MF:C24H38O4, C24H38O4
- EINECS No.:201-557-4
- Purity:99.5% Min
- Type:Plastizer
- Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
- MOQ::10 Tons
- Package:25kg/drum
- Payment:T/T
- Application:PVC Plasticizer
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We reported previously that inhibition of aldehyde dehydrogenase (ALDH) and aldehyde/aldose reductase Sullivan P, Cooney A, Goldstein DS. (2014) Benomyl, aldehyde
The Catecholaldehyde Hypothesis for the
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:Dop
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:99.5%, 99% min
- Type:DOP
- Usage:PVC Products, Coating Auxiliary Agents, Leather Auxiliary Agents,
- MOQ:200kgs
- Package:200kgs/battle
- Volume Resistivity:50
- Item:T/T,L/C
DOPAL is autotoxic, in that it can harm the same cells in which it is produced. Normally, DOPAL is detoxified by aldehyde dehydrogenase (ALDH)-mediated conversion to 3,4-dihydroxyphenylacetic acid (DOPAC), which rapidly exits
Typically, toxic aldehydes are metabolized by aldehyde dehydrogenase (ALDH). 5-HIAL is oxidized to 5-hydroxyindole acetic acid (5-HIAA) by ALDH . DOPAL can undergo carbonyl