[Determination of Plasticizer DEHP Released from Medical Hungary

Analytical methods for the determination of DEHP plasticizer

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
Other Names:Plasticizer
Purity:99.0%Min
Type:Plastizer
Usage:Plasticizer
MOQ:25kg/bag
Package:200kg/drum
Advantage:Stable

As plasticizers are not chemically bound to PVC, they can be released from the medical device during contact with blood, enteral or total parenteral nutrition admixtures, or

Download Citation Determination of Plasticizer DEHP Released from Medical Injection Equipment To established an effective GC-MS /MS method for the contents

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Analytical methods for the determination of DEHP plasticizer

Classification:Chemical Auxiliary Agent
Other Names:Plasticizer
Purity:99%, 99%
Type:Adsorbent, plasticizer
Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals
MOQ:200kgs
Package:200kgs/battle
Quality control:COA ,SDS,TDS

Until 2010, diethylhexylphthalate (DEHP) was the plasticizer most commonly used to soften PVC medical devices (MDs), because of a good efficiency/cost ratio. In flexible plasticized PVC,

The results from the determination of the DEHP released will be compared with the limits derived from toxicological data for the parenteral exposure route and certain population groups, and the

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Leaching of plasticizers from PVC medical devices: A

Classification:Chemical Auxiliary Agent
Other Names:Plasticizer
Purity:99.5% min.
Type:Adsorbent, Carbon Black
Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals
MOQ:25kg/bag
Package:200kg/drum
Color:colorless

The use of DEHP in PVC medical devices is now limited to 0.1% by mass of plasticised material by the European Regulation N o 2017/245 on We used the HPLC

, 198, pp.377-389. Alternative plasticizers, Medical devices, SPE-LC-MS/MS, Human biomonitoring, urinary

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Analytical methods for the determination of DEHP plasticizer

Classification:Chemical Auxiliary Agent
Other Names:Plasticizer
Purity:99%
Type:Plastizer
Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Model Number:Plasticizer

Europe PMC is an archive of life sciences journal literature.

Due to adverse health effects, di-(2-ethylhexyl) phthalate (DEHP), a plasticizer used to soften plastic medical devices (PMDs), was restricted, and gradually replaced by alternative

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Analytical methods for the determination of DEHP plasticizer

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
Other Names:Plasticizer
Purity:99%min
Type:Plasticizer, Dioctyl Phthalate
Usage:Leather Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:1000KG
Package:25kg/drum
Sample:Availabe
Item:T/T,L/C
Application:Plasticizer
Quality control:COA ,SDS,TDS
Delivery:Within 7-15 Days

Until 2010, diethylhexylphthalate (DEHP) was the plasticizer most commonly used to soften PVC medical devices (MDs), because of a good efficiency/cost ratio. In flexible

The amount of DEHP released from both laboratory-produced PVC films and commercially available PVC products was measured to elucidate the potential risks associated with its real-world applications.

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What is DEHP?
DEHP, or diethylhexylphthalate, was the most commonly used plasticizer for softening PVC medical devices until 2010. It was favored for its good efficiency/cost ratio. However, in flexible plasticized PVC, phthalates like DEHP are not chemically bound to PVC and they are released into the environment, potentially coming into contact with patients.
How much DEHP can be used in PVC medical devices?
The use of DEHP in PVC medical devices is now limited to 0.1% by mass of plasticised material by the European Regulation N o 2017/245 on medical devices .
Can plasticizers be released from a medical device?
As plasticizers are not chemically bound to PVC, they can be released from the medical device during contact with blood, enteral or total parenteral nutrition admixtures, or lipophilic drugs, which might lead to unwanted patient exposure , , .
What plasticizer alternatives are present in medical devices?
Analytical methods for the determination of plasticizer alternatives to DEHP in medical devices: a review. Until 2010, diethylhexylphthalate (DEHP) was the most commonly used plasticizer in medical devices due to its good efficiency/cost ratio. However, the passage does not provide information about the specific alternatives.
Are DEHP and glucuronide conjugates a biomarker of plasticizer exposure in human urine?
Our study aimed to develop a novel sensitive and selective method to simultaneously identify and quantify DEHP and 17 other plasticizer metabolites (free or glucuronide conjugates), which are specific biomarkers of DEHTP, TOTM, DINP, DINCH and DEHA exposure in human urine.
Can NMR detect traces of DEHP in PVC medical devices?
Genay et al. used NMR to identify traces of DEHP in PVC medical devices presented as DEHP-free, i.e., with an amount lower than 0.1% . However, Lutyten et al. identified several drawbacks, including low sensitivity, while working on the quantification of different plasticizers present in PVC tubes.