Determination of release of phthalate plasticizers in saliva simulant

  • Determination of release of phthalate plasticizers in saliva simulant
  • Determination of release of phthalate plasticizers in saliva simulant
  • Determination of release of phthalate plasticizers in saliva simulant
  • How are phthalates analyzed in a migration test from PVC toys?
  • In this Application Note, the analysis of phthalates in a migration test from PVC toys is performed using the Agilent 1260 Infi nity Analytical SFC System in combination with an Agilent 6130 Single Quadrupole LC/MS.
  • Which phthalate is detected in GC-MS?
  • At least one PAE was detected in 81% of samples, and di-n-octyl phthalate was found in higher concentration, achieving the migration of almost 30 μg per g of sample. GC-MS; Pa-DPX; Parallel-disposable pipette extraction; Phthalate migration; Saliva simulant. Copyright © 2020 Elsevier B.V. All rights reserved.
  • What are phthalic acid esters?
  • Phthalic acid esters (“phthalates”) are the most commonly used plasticizers in polyvinyl chloride (PVC) based products due to their compatibility and softening capability . The plasticiser content can be up to 50% by weight.
  • Can mixed isomer phthalates be analyzed?
  • It poses a signifi cant analytical challenge to perform the analysis of these mixed isomer phthalates.
  • What are phthalates used for?
  • Phthalates form a group of well known plasticizers that are often applied to soften polymers, such as PVC, in toys. High molecular weight phtha- lates are used as polymer additives. Phthalates are not chemically bound to PVC and can leach out or evaporate into the environment.
  • How accurate are phthalate ion abundance ratios?
  • Replicate measurements (n=15) on the ion abundance ratios for each phthalate was determined to calculate the precision of the calibration, and the relative standard deviations of the qualifier to the quantifying ion. The relative standard deviations on the relative abundances did not exceed 10% for all the phthalates tested.

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