Diethyl phthalate (DEP) Switzerland

  • Diethyl phthalate (DEP) Switzerland
  • Diethyl phthalate (DEP) Switzerland
  • Diethyl phthalate (DEP) Switzerland
  • What is diethyl phthalate (DEP)?
  • Diethyl phthalate (DEP) is widely used in many commercially available products including plastics and personal care products. DEP has generally not been found to share the antiandrogenic mode of action that is common among other types of phthalates, but there is emerging evidence that DEP may be associated with other types of health effects.
  • How much diethyl phthalate is in food?
  • Based on the levels of diethyl phthalate found in food by Castle et al. (1988), Kamrin & Mayor (1991) estimated a total daily dietary exposure to diethyl phthalate of 4 mg, assuming daily ingestion of 1 kg of cellulose acetate-wrapped food containing 4 mg diethyl phthalate/kg.
  • Is diethyl phthalate a potent developmental toxicant?
  • DEP is not a potent developmental toxicant, although skeletal variations and decreased growth were observed. Low dose studies reported large magnitudes of effect but significant concerns for bias were identified. Diethyl phthalate (DEP) is widely used in many commercially available products including plastics and personal care products.
  • Where can I get a book about diethyl phthalate?
  • Diethyl phthalate. All rights reserved. Publications of the World Health Organization can be obtained from Marketing and Dissemination, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel: +41 22 791 2476; fax: +41 22 791 4857; email: [email protected]).
  • What does a diethyl phthalate expert do?
  • These experts collectively have knowledge of diethyl phthalate’s physical and chemical properties, toxicokinetics, key health end-points, mechanisms of action, human and animal exposure, and quantification of risk to humans.
  • Where is diethyl phthalate found?
  • Diethyl phthalate has been found at a median concentration of <10 μg/litre in 10% of the industrial effluent samples and in 3.0% of the ambient water samples in the Storage and Retrieval (STORET) database maintained by the US Environmental Protection Agency (EPA) (Staples et al., 1985).

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