DINP-n Chemistry Argentina Israel

  • DINP-n Chemistry Argentina Israel
  • DINP-n Chemistry Argentina Israel
  • DINP-n Chemistry Argentina Israel
  • Is DINP antiandrogenic?
  • Several studies have reported that DiNP is antiandrogenic at specific doses 9, 42, 43. The present study shows that DiNP exposure causes a marginal decrease in testosterone levels in the colon compared to control, suggesting that DiNP also may have some antiandrogenic properties in the GIT.
  • How many toxicity data are there in a DINP mixture?
  • Most toxicity data generated so far refer to two commercial DINP mixtures consisting of more than 100 compounds: Jayflex® brand DINP 68515-48-0 and DINP CAS No. 28553-12-0. This variability poses the following problems: Differences in the toxicity of individual components within technical mixtures cannot be identified .
  • What CAS number is DINP toxicity?
  • In a 21-d study to assess the toxicity of DINP identified under three CAS numbers, 71549-78-5, 68515-48-0, and 28553-12-0, Fischer Table 5. Acute toxicity of DINP in mammals. F-344 rats were fed diets containing 0%, 0.6%, 1.2%, or 2.5% of the plasticizer.
  • What is DINP used for?
  • DiNP is primarily used to produce flexible plastics and has replaced di-2-ethylhexyl phthalate (DEHP) in some plastics, though not in medical products. DiNP is widely used in such products as toys, flooring, gloves, drinking straws, garden hoses, and in sealants used for food packaging.
  • What is DINP genotoxicity?
  • DINP (NTP 2000). MutagenicitylGenotoxicity. DINP was tested for genotoxicity in a battery of in vitro bacterial and mammalian cell assays, and the data were summarized in several studies (Omarie 1976; CMA 1986; Hazelton Biotechnologies Company 1986; EG&G Mason Research Institute 1982a,b).
  • How many t of DINP are produced in the United States?
  • In 1990,93,575 t of DINP (CAS No. 28553-12-0) were produced and sold in the U.S. (Kirk Othmer 1996), and currently DINP accounts for roughly 10%-15% of total U.S. production ofDAPs, i.e., 90,000-140,000 tJyr (CEH 2000).

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