SKF-83566 Dopamine D1/D5 Receptor
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:Dop
- MF:C24H38O4, C24H38O4
- EINECS No.:201-557-4
- Purity:99%
- Type:Liquid, plasticizer
- Usage:Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ::10 Tons
- Package:25kg/drum
- Place of Origin::China
SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine
SCH23390 is a widely used D 1 dopamine receptor (D 1 R) antagonist that also elicits some D 1 R-independent effects. We previously found that the benzazepine, SKF83959,
Dopamine D1/D5 Receptor Antagonists with
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:DOP/Dioctyl Phthalate
- MF:C24H38O4, C24H38O4
- EINECS No.:201-557-4
- Purity:99%min
- Type:non-toxic calcium zinc stabilizer
- Usage:PVC shoe, PVC Air Blowing/Expander PVC/DIP Shoes
- MOQ:200kgs
- Package:200kgs/battle
- Advantage:Stable
Benzazepines 1 and 2 (SCH 23390 and SCH 39166, respectively) are two classical benzazepine D1/D5 antagonists, with Ki values 1.4 and 1.2 nM, respectively. Compound 2 has been in human clinical trials for a variety of
However, selective activation of D1/D5 (D1-like) dopamine receptors may enable robust activation of motor function while avoiding AEs related to D2/D3 receptor agonism. Full D1/D5 receptor
LE 300 Dopamine D1 and D5 Receptor Antagonists: R&D
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:Liquid DOP, DOP oil
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:≥99.5%
- Type:Adsorbent, Carbon Black
- Usage:Coating Auxiliary Agents
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Application:PVC Plasticizer
LE 300 is a potent and selective dopamine D 1 receptor antagonist (K i values are 0.08 1.9 nM and 6 45 nM for D 1 and D 2 receptors respectively). Also displays moderate affinity for the 5
Male BALB/c mice injected with quetiapine every other day and pretreated with the D1 receptor antagonist SKF-35866 in the following experiments found a significant increase in the preference to the and
SCH 23390: the first selective dopamine D1-like receptor
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:DOP, diocty phthalate, 1,2-phthalate
- MF:C6H4(COOC8H17)2
- EINECS No.:201-557-4
- Purity:99
- Type:Chemical additives, Chemical dop plasticizer 99%
- Usage:PVC shoe, PVC Air Blowing/Expander PVC/DIP Shoes
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Shape:Powder
- Model:Dop Oil For Pvc
SCH 23390, the halobenzazepine (R)-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5- tetrahydro-1H-3-benzazepine, is a highly potent and selective dopamine D1-like receptor
Agonist to the D1, D2, D3, D4, D5 dopamine receptors. Interacts on the synaptic terminals, causing neuronal excitation or inhibition at the target neuron: Hemodynamic imbalances
Dopamine D1/D5 receptor antagonists with improved
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:Dioctyl Phthalate
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:99%, 99%
- Type:Adsorbent
- Usage:Plastic Auxiliary Agents, Plasticizer
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Place of Origin::China
- Advantage:Stable
Feb 10, 2005Replacement of the phenol group of 2 with an indole ring generated the first potent D1/D5 antagonist 11b. Further optimization led to the synthesis of very potent
Understanding the intricate role of dopamine D1–D5 receptors is pivotal in addressing the challenges posed by the aging global population, as well as by social stress and advancing therapeutic interventions. Central to diverse