good stability Development Application Services-DOTP

  • good stability Development Application Services-DOTP
  • good stability Development Application Services-DOTP
  • good stability Development Application Services-DOTP
  • What is a DOTP plasticizer?
  • Its primary function is to enhance the flexibility, durability, and workability of polyvinyl chloride (PVC) products while offering several advantages over traditional phthalate-based plasticizers. DOTP is known for its excellent thermal stability, low volatility, and high plasticizing efficiency.
  • What is DOTP used for?
  • DOTP is known for its excellent thermal stability, low volatility, and high plasticizing efficiency, making it ideal for applications requiring stringent safety and regulatory compliance.DOTP finds extensive use in the production of flexible PVC products, including medical devices, toys, food packaging, and automotive interiors.
  • Is DOTP (DEHT) eco-friendly?
  • To fully understand the environmental impact of a particular product, the entire life cycle needs to be considered: without data to support the claim, saying DOTP (DEHT) is “eco-friendly” is not accurate. DOTP (DEHT) was developed in 1949 and patented in 1953 by ExxonMobil but never commercialized for a good reason.
  • How much ASE & DOTP are in simulants for aqueous and low alcohol foods?
  • Migration of ASE, COMGHA, DINCH, DOTP, DEHCH, and TOTM in simulants for aqueous and low alcohol foods ranged from <0.02 to 0.165 mg/kg. Human biomonitoring data are available for DINCH, DOTP, DEHA, DINA, and TOTM, and indicate that total exposures from all sources are below regulatory thresholds.
  • Are physiological based pharmacokinetic models available for DOTP?
  • Recently, physiological based pharmacokinetic models (PBPK) were published for DINCH (McNally et al., 2019) and for two ortho-phthalates, DINP (Campbell et al., 2020) and di-propyheptyl phthalate (DPHP, McNally et al., 2021). We understand that a model for DOTP also is under development.

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