good stability Dopamine D1/D5 Receptor Antagonist

Dopamine D1–D5 Receptors in Brain Nuclei:

Classification:Chemical Auxiliary Agent
CAS No.:117-84-0
Other Names:DOP, Dioctyl phthalate
MF:C24H38O4, C24H38O4
EINECS No.:201-557-4
Purity:99%min
Type:pvc additive
Usage:Rubber Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Place of Origin::China

Understanding the intricate role of dopamine D1–D5 receptors is pivotal in addressing the challenges posed by the aging global population, as well as by social stress and advancing therapeutic interventions. Central to diverse

Benzazepines 1 and 2 (SCH 23390 and SCH 39166, respectively) are two classical benzazepine D1/D5 antagonists, with Ki values 1.4 and 1.2 nM, respectively. Compound 2 has been in human clinical trials for a variety of

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Physiological and Functional Basis of Dopamine Receptors

Classification:Chemical Auxiliary Agent
CAS No.:117-84-0
Other Names:Dioctyl Phthalate DOP
MF:C24H38O4
EINECS No.:201-557-4
Purity:99.9%
Type:non-toxic calcium zinc stabilizer
Usage:Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Place of Origin::China
Item:T/T,L/C

D1-like dopamine receptor expression and its functions. The D1-like receptor family consists of 2 types of GPCRs that include the D1 and D5 receptors, with a higher density in the striatum or

Dopamine acts as an essential neurotransmitter whose signaling is conducted through five G protein-coupled receptors (GPCRs), dopamine D1 to D5 receptors

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Dopamine D1/D5 receptor antagonists with improved

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
cas no 117-84-0
Other Names:DOP, diocty phthalate, 1,2-phthalate
MF:C24H38O4, C24H38O4
EINECS No.:201-557-4
Purity:99.5% Min
Type:Chemical additives, Chemical dop plasticizer 99%
Usage:Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Shape:Powder
Place of Origin::China
Advantage:Stable

Feb 10, 2005Replacement of the phenol group of 2 with an indole ring generated the first potent D1/D5 antagonist 11b. Further optimization led to the synthesis of very potent

The DA D1-like receptor family includes D1 and D5 receptors whereas the D2 receptor class includes D2, D3, D4 subtypes. The molecular structures of these classes of DA receptors also

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Recent advances in dopaminergic strategies for

Classification:Chemical Auxiliary Agent
CAS No.:117-84-0
Other Names:Chemical Auxiliary Agent
MF:C24H38O4
EINECS No.:201-557-4
Purity:99.5%, 99% min
Type:Oil drilling
Usage:Leather Auxiliary Agents, Plastic Auxiliary Agents, Plasticizer
MOQ::10 Tons
Package:25kg/drum
Model:Dop Oil For Pvc

A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/d5 receptor partial agonist (pf-06412562) in patients with stable schizophrenia. J Psychopharmacol. 2019;33:1237–47.

Dopamine controls various physiological functions in the brain and periphery by acting on its receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors involved in the regulation of motor activity

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Pharmacology of Dopamine and Its Receptors SpringerLink

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
cas no 117-84-0
Other Names:DOP, diocty phthalate, 1,2-phthalate
MF:C24H38O4
EINECS No.:201-557-4
Purity:≥99.5%
Type:Plasticizer
Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
MOQ:200kgs
Package:200kgs/battle
Place of Origin::China
Item:T/T,L/C

The physiological actions of dopamine are mediated by its interaction with dopamine receptors that are localized over dopaminergic synapses. There are five types of

Dopamine D1 receptor (D1R) is an important drug target implicated in many psychiatric and neurological disorders. To assess the stability of the D1 active structure the

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