Immobile plasticizer in flexible PVC France

  • Immobile plasticizer in flexible PVC France
  • Immobile plasticizer in flexible PVC France
  • Immobile plasticizer in flexible PVC France
  • Where can plasticizers be used?
  • The plasticizer can migrate from PVC-based devices and storage bags into physiological fluids, however, and has been detected in storage media such as blood, plasma, serum, drug solutions and fatty foods 2, 3, 4, as well as in the bodies of patients undergoing haemodialysis and transfusion 5.
  • Can plasticizer migration be prevented?
  • When the surfaces of flexible PVC sheets were similarly modified, we found that plasticizer migration could be prevented completely, as it was in PVC tubes. How-ever, modification led to a decrease in the stress (about 8 per cent) and strain (about 28 per cent) at the breaking point for PVC sheets.
  • Can plasticizers leach out from pPVC?
  • Since plasticizers in PVC are not chemically bound to polymer backbone, they can leach out when a pPVC containing medical device comes into contact with body fluids such as blood, serum, saliva and intravenous infusion liquids , . Leaching of plasticizers from pPVC becomes a serious problem because of the two following aspects.
  • Are plasticizers toxic?
  • As plasticizers are not chemically bound to PVC they can easily migrate to surrounding media such as saliva, blood, plasma or serum resulting in undesirable toxic effects.
  • Is plasticized polyvinyl chloride harmful?
  • However, an application of common plasticized polyvinyl chloride (pPVC) is accompanied by an adverse phenomenon, specifically by the non-negligible and potentially harmful migration of plasticizers into the surrounding media as they are not covalently bound to PVC.
  • Why is PVC used in medicine?
  • The dominant position in medicine is held by PVC also due to the flexibility of its final products. This property is achieved by the high presence of added plasticizers achieving up to 40 % while PVC itself contributes by approximately 55 %, the remainder is formed of various additives.

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