Dopamine D1/D5 Receptor Antagonists with
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:DOP Bis(2-ethylhexyl) phthalate
- MF:C24H38O4, C24H38O4
- EINECS No.:201-557-4
- Purity:99.5% min.
- Type:Plasticizer Colorless Oily Liquid DOP for pvc and rubber
- Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Advantage:Stable
- Keywords:Plasticizer Dop
Benzazepines 1 and 2 (SCH 23390 and SCH 39166, respectively) are two classical benzazepine D1/D5 antagonists, with Ki values 1.4 and 1.2 nM, respectively. Compound 2 has been in human clinical trials for a variety of
A highly potent and selective dopamine D1-like receptor antagonist with a K i of 0.2 and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5
SCH 23390: the first selective dopamine D1-like receptor
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:Dioctyl Phthalate
- MF:C6H4(COOC8H17)2
- EINECS No.:201-557-4
- Purity:99 %
- Type:Oil drilling
- Usage:PVC shoe, PVC Air Blowing/Expander PVC/DIP Shoes
- MOQ:200kgs
- Package:200kgs/battle
- Advantage:Stable
- Keywords:Plasticizer Dop
The inference from a majority of studies is that the activation of dopamine D1 receptors facilitates seizure activity, whereas activation of D2 receptors may inhibit the development of seizures.
Feb 10, 2005Replacement of the phenol group of 2 with an indole ring generated the first potent D1/D5 antagonist 11b. Further optimization led to the synthesis of very potent
The classical D1 dopamine receptor antagonist SCH23390 is
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:Dop
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:99.9%
- Type:Plasticizer
- Usage:Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Textile Auxiliary Agents, Leather Auxiliary Agent,Plastic Auxiliary Agent,
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Application:PVC Plasticizer
SCH23390 is a widely used D1 dopamine receptor (D1R) antagonist that also elicits some D1R-independent effects. We previously found that the benzazepine, SKF83959,
Sep 9, 2003To extend our investigation to the potential role of D 5 receptors on motor activity, we also analyzed the motor effects of SCH 23390, a D 1 /D 5 receptor antagonist, in both WT
Aminoalkyl)benzazepine Analogs: Novel Dopamine D1
- Classification:Chemical Auxiliary Agent
- CAS No.:117-84-0
- Other Names:DiOctyle Phthalate DOP
- MF:C24H38O4
- EINECS No.:201-557-4
- Purity:99.9%
- Type:Plasticizer, Dioctyl Phthalate
- Usage:Plasticizer
- MOQ::10 Tons
- Package:25kg/drum
- Shape:Powder
- Place of Origin::China
- Advantage:Stable
Oct 1, 1995Dopamine D1/D5 Receptor Antagonists with Improved Pharmacokinetics: Design, Synthesis, and Biological Evaluation of Phenol Bioisosteric Analogues of Benzazepine D1/D5
A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/d5 receptor partial agonist (pf-06412562) in patients with stable schizophrenia. J Psychopharmacol. 2019;33:1237–47.
Therapeutic Potential of Dopamine and Related Drugs as
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- cas no 117-84-0
- Other Names:DOP
- MF:C24H38O4, C24H38O4
- EINECS No.:201-557-4
- Purity:99%min
- Type:Carbon Black
- Usage:Plastic Auxiliary Agents, Textile Auxiliary Agents
- MOQ:200kgs
- Package:200kgs/battle
- Shape:Powder
- Advantage:Stable
- Keywords:Plasticizer Dop
Agonist to the D1, D2, D3, D4, D5 dopamine receptors. Interacts on the synaptic terminals, causing neuronal excitation or inhibition at the target neuron: Ergoline derivative, agonist to
Understanding the intricate role of dopamine D1–D5 receptors is pivotal in addressing the challenges posed by the aging global population, as well as by social stress and advancing therapeutic interventions. Central to diverse