Plasticizer Migration Study by Teknor Apex Ranks Phthalates Saudi Arabia

  • Plasticizer Migration Study by Teknor Apex Ranks Phthalates Saudi Arabia
  • Plasticizer Migration Study by Teknor Apex Ranks Phthalates Saudi Arabia
  • Plasticizer Migration Study by Teknor Apex Ranks Phthalates Saudi Arabia
  • Do plasticizers migrate in dynamic conditions?
  • Under identical dynamic experimental conditions, the plasticizers demonstrated different migration abilities within the first 24 h of contact. Regardless the flow rate, DINP and DINCH had the highest degrees of migration in dynamic conditions compared to TOTM and DEHT.
  • Does the migration of plasticizers vary with the type of medical device?
  • The results highlight that the migration of plasticizers varies greatly with the type of medical device.
  • Does a higher flow rate affect plasticizer migration kinetics?
  • From a clinical view, higher speeds led to higher amounts of plasticizers released to inpatients for a fixed contact time of 24h. On the other side, from a physicochemical view, there was no significant difference of the migration kinetic in relation to the flow rate at each contact point of a same medical device.
  • Do plasticizers migrate from the infusion sets at 24h?
  • Comparison of the migration of plasticizers from the infusion sets at 24h according the flow rate (n = 3, mean +/- standard deviation). Under identical dynamic experimental conditions, the plasticizers demonstrated different migration abilities within the first 24 h of contact.
  • Are phthalate plasticizers better than phthalates?
  • Phthalate plasticizers contact with an unplasticized surface showed more easier to migration. The further studies suggested that all ILs showed good thermodynamic compatibility, excellent leaching and migration resistance than phthalates .
  • How can plasticizer migration be inhibited?
  • Therefore, migration of plasticizer can be inhibited by the three following ways: (1) using plasticizers with higher molecular weight and hyperbranched degree, (2) increasing the interaction between plasticizer and PVC matrix, (3) modifying or coating the surface of soft PVC by physical or chemical methods for restricting the plasticizer migration.

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