Weight of Evidence Indicates That DINP Should Not Be Listed South Africa

  • Weight of Evidence Indicates That DINP Should Not Be Listed South Africa
  • Weight of Evidence Indicates That DINP Should Not Be Listed South Africa
  • Weight of Evidence Indicates That DINP Should Not Be Listed South Africa
  • Does the DINP category meet the EPCRA toxicity criterion?
  • The updated hazard assessment demonstrates that the proposed DINP category meets the EPCRA toxicity criterion because the members of the category can reasonably be anticipated to cause cancer and serious or irreversible chronic health effects in humans; specifically, developmental, kidney, and liver toxicity.
  • What is the hazard assessment for DINP?
  • The proposed rule was based on information contained in the hazard assessment for DINP that was developed in response to the petition. EPA proposed to list the DINP category based on cancer and serious or irreversible chronic health effects including liver, kidney, and developmental toxicity.
  • Is DINP a hazard?
  • EPA has updated its hazard assessment for DINP and is proposing to add DINP as a category defined to include branched alkyl di-esters of 1,2 benzenedicarboxylic acid in which alkyl ester moieties contain a total of nine carbons.
  • Does DINP cause peroxisome proliferation?
  • It is now well-accepted that peroxisome proliferation is specific to rodents and in the monkey study (Huntington Life Science, 1998) the data obtained following oral administration of DINP for 13 weeks provide no evidence that the compound caused induction of peroxisome proliferator.
  • Can DINP be used in toys and childcare articles?
  • A recent publication of the Danish Environmental Protection Agency (EPA) (Danish EPA, 2009) does not bring any new critical information on the use of DINP in toys and childcare articles which may affect the exposure and risk assessments that were conducted in the framework of the EU Risk Assessment Report.
  • Does DINP cause cancer?
  • EPA proposes to conclude that the available cancer data provides a sufficient basis for listing DINP on the EPCRA section 313 toxic chemicals list pursuant to EPCRA section 313 (d) (2) (B) (i) because it demonstrates that DINP can reasonably be anticipated to cause cancer in humans. 2. What chronic developmental toxicity data were found for DINP?

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