What health effects can DBP cause in laboratory animals

The overview of current evidence on the reproductive

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The embryotoxic effects of DBP on laboratory animals included mainly an increase in fetal resorption and a decrease in live births. -androgenic effects; however, there are also

Phthalates have been suggested to cause several detrimental health effects, in particular as endocrine disruptors and reproductive toxicants with anti-androgenic properties [5,6]. Di-n

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The overview of current evidence on the

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CAS No.:84-74-2
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The embryotoxic effects of DBP on laboratory animals included mainly an increase in fetal resorption and a decrease in live births. consequently causes adverse health effects in an intact

5. What health effects can DBP cause in laboratory animals? If DBP is swallowed, about 90% is rapidly absorbed and excreted in the urine within 48 hours. Very little is eliminated via the

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Short term exposure to di-n-butyl phthalate (DBP) disrupts

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Animals treated with the high doses also showed disruptions in steroidogenic enzyme expression, but lacked alterations in antral follicle number and disruptions in apoptosis gene expression.

Animal experiments suggested DBP could induce a spectrum of TDS-related disorders 27,28,29, and the adverse effects of DBP on germ cells were observed in a human fetal testis xenografts model 30

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Phthalate Di-butyl phthalate GreenFacts

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CAS No.:84-74-2
Other Names:DBP
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5. What health effects can DBP cause in laboratory animals? DBP is well absorbed by the body following ingestion or contact with the skin. The extent of absorption when DBP is breathed in is not known but it is likely to be well

The animal experiment was performed in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and was approved by the Animal

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Phthalates and Cumulative Risk Assessment The

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in laboratory animals have shown that exposure can cause adverse health effects, including effects on development of the male reproductive system. Few data are available on the health effects of phthalates in humans, but studies show widespread human exposure to phthalates. The United States and the European Union have passed legislation

The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of di-n-butyl phthalate. It contains

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