EPA Issues Draft Risk Evaluation for Diisononyl phthalate
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:68515-48-0
- Other Names:DINP
- MF:C26H42O4
- EINECS No.:249-079-5
- Purity:99.6%
- Type:New Type Environment DINP Plasticizer
- Usage:Plastic Auxiliary Agents
- MOQ:1000KG
- Package:25kg/drum
- Model Number:DINP
EPA received and granted manufacturer requests for risk evaluations of DINP and for diisodecyl phthalate (DIDP) in 2019. EPA released the draft risk evaluation for DIDP in May
PUBLIC RELEASE DRAFT May 2024 Page 5 of 12 103 SUMMARY 104 EPA gathered and evaluated physical and chemical property data and information according to the 105 process
Subacute exposure to di-isononyl phthalate alters the
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:28553-12-0
- Other Names:Plasticizer DINP
- MF:C26H42O4, C26H42O4
- EINECS No.:271-090-9
- Purity:99.9%
- Type:DINP
- Usage:Plastic Auxiliary Agents, Plasiticizer
- MOQ:200kgs
- Package:200kgs/battle
- Package:200kg/drum
Di-isononyl phthalate (DiNP), a common plasticizer used in polyvinyl chloride products, exhibits endocrine-disrupting capabilities. It is also toxic to the brain, reproductive
2.1. Production and Composition of DINP. Commercially available DINP is a complex mixture of diesters of o-phthalic acid containing C8–C10 (C9 rich) alkyl side chains.In
Selecting Adequate Exposure Biomarkers of Diisononyl
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:68515-48-0
- Other Names:Di-isononyl phthalate
- MF:C26H42O4 Diisononyl Phthalate
- EINECS No.:249-079-5
- Purity:99.5% Diisononyl Phthalate
- Type:Adsorbent
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Plastic Auxiliary Agents, Rubber Auxiliary Agents
- MOQ:200kgs
- Package:200kgs/battle
- Function:PVC Plasticizer
BackgroundHigh-molecular-weight phthalates, such as diisononyl phthalate (DINP) and diisodecyl phthalate (DIDP), are used primarily as polyvinyl chloride
risk evaluations to be conducted under the Toxic Substances Control ACt (TSCA) of Di-isodecyl Phthalate (DIDP) and Di-isononyl Phthalate (DINP). While the agency published separate
Peer Review of EPA’s Draft Risk Evaluation for Di-isodecyl
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:28553-12-0
- Other Names:DINP
- MF:C26H42O4
- EINECS No.:271-090-9
- Purity:>99.5%
- Type:DINP
- Usage:Plastic Auxiliary Agents, Plasiticizer
- MOQ:1000KG
- Package:25kg/drum
- Certification:ISO9001
In May 2024, EPA released for public comment and peer review the draft risk evaluation for Di-isodecyl phthalate (DIDP) and the draft hazard assessment for Di-isononyl phthalate (DINP)
di-isononyl phthalate (DINP) • di-isodecyl phthalate (DIDP) • di-n-butyl phthalate (DBP) • butyl benzyl phthalate (BBP) • di-n-octyl phthalate (DnOP) • di-n-hexyl phthalate (DnHP) Phthalates are a group of similar chemicals widely used to soften and increase the flex-
ENVIRONMENTAL PROTECTION AGENCY Meeting;
- Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
- CAS No.:68515-48-0
- Other Names:Plasticizer DINP
- MF:C26H42O4
- EINECS No.:249-079-5
- Purity:99%
- Type:Adsorbent
- Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Textile Auxiliary Agents
- MOQ:200kgs
- Package:200kgs/battle
- Model Number:DINP
for Di-isodecyl Phthalate (DIDP) and the draft physical chemical, fate, and hazard assessments for Di-isononyl Phthalate (DINP) prepared under the Toxic Substances Control Act (TSCA). The draft documents will also be submitted to the Science Advisory Committee on Chemicals (SACC) for peer review.
Di-isodecyl Phthalate (DIDP) (1,2-Benzenedicarboxylic acid, 1,2-diisodecyl ester and 1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich) CASRN 26761-40-0 and 68515-49-1 DINP Di-isononyl phthalate ECHA European Chemicals Agency EC European Commission EC x
- When did EPA request a risk evaluation for Diisodecyl phthalate (DIDP)?
- EPA received and granted manufacturer requests for risk evaluations of DINP and for diisodecyl phthalate (DIDP) in 2019. EPA released the draft risk evaluation for DIDP in May 2024 and requested peer review on the DINP human health hazard assessment at that time.
- What are high molecular-weight phthalates (DINP) and diisodecyl phthalate (D?
- High molecular-weight phthalates, such as diisononyl phthalate (DINP), and diisodecyl phthalate (DIDP), are widely used as plasticizers in the manufacturing of polymers and consumer products. Human biological monitoring studies have employed the metabolites of DINP and DIDP as biomarkers to assess human exposure.
- What is diisononyl phthalate (DINP)?
- Policies and ethics Diisononyl phthalate (DINP) is one of the widely used dialkyl phthalate (DAPs) softeners in the production of flexible polyvinyl chloride (PVC) plastics, copolymers, and resins. These phthalate plasticizers are incorporated into the PVC polymer matrix to impart...
- Does DINP cause phthalate syndrome?
- However, DINP does have the potential to cause phthalate syndrome. Therefore, EPA is including DINP in its cumulative risk assessment along with five other phthalate chemicals that have the potential to cause phthalate syndrome, while DIDP is excluded from the cumulative risk assessment.
- Does Di (isodecyl) phthalate induce peroxisomal proliferation?
- Additional studies were also conducted on di (isodecyl) phthalate (DIDP), a structurally related substance that also induces peroxisomal proliferation, although it has not been tested in a carcinogenicity bioassay.
- Does Di (isononyl) phthalate cause liver tumors?
- Recently there have been reports of liver and kidney tumors in rodents following long-term exposure to di (isononyl) phthalate (DINP). Mechanistic studies suggested that the liver tumors were a consequence of peroxisomal proliferation, whereas the kidney tumors (found only in male rats) were associated with induction of alpha (2u)-globulin.