Evaluation of new scientific evidence concerning DINP and DIDP Sri Lanka

Evaluation of new scientific evidence concerning DINP

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:28553-12-0
Other Names:DINP
MF:C26H42O4 Diisononyl Phthalate
EINECS No.:271-090-9
Purity:>99.5%
Type:DINP
Usage:Plastic Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Storage:Dry Place

Evaluation of new scientific evidence concerning DINP and DIDP 7 1. Conclusions ECHA concluded that a risk from the mouthing of toys and childcare articles with DINP and DIDP

It is not anticipated that mouthing of erasers containing DINP or DIDP would lead to a considerable risk for children. Furthermore, no risk is expected from combined exposure. 4. to

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ECHA’s final review report on DINP and DIDP

Classification:Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:Plasticizer DINP
MF:C26H42O4
EINECS No.:249-079-5
Purity:99%
Type:PVC resin plasticizer
Usage:Plastic Auxiliary Agents, Plasiticizer
MOQ:200kgs
Package:200kgs/battle
Model Number:DINP

the European Chemical Agency (ECHA) published its final report on the “Evaluation of new scientific evidence concerning DINP and DIDP in relation to entry 52 of

Evaluation of new scientific evidence concerning DINP and DIDP In relation to entry 52 of Annex XVII to REACH Regulation (EC) No 1907/2006 Final review report annankatu 18, p.o. box

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Evaluation of new scientific evidence concerning DINP

Classification:Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:Diisononyl phthalate
MF:C26H42O4 Diisononyl Phthalate
EINECS No.:249-079-5
Purity:99.5%
Type:Plasiticizer
Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:1000KG
Package:25kg/drum
Function:PVC Plasticizer

has other version or edition 3687948 Committee for Risk Assessment (RAC) Opinion on the ECHA’s draft review report on “Evaluation of new scientific evidence

While EPA will not be requesting peer review on the full risk evaluation for DINP, the peer review on the DINP hazard assessments will cover all the scientific questions that

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Comments from Scientists, Academics, and Clinicians on

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:Plasticizer DINP
MF:C26H42O4, C26H42O4
EINECS No.:249-079-5
Purity:99%
Type:Plasiticizer
Usage:Plastic Auxiliary Agents, Plasiticizer
MOQ:1000KG
Package:25kg/drum
Shelf life:2 Years

account for and incorporate the scientific evidence. Critical aspects of the present draft also warrant further SACC review before the DINP risk evaluation is finalized. Multiple

that DINP (and DIDP, DNOP) shall not be used as a constituent of greater than 0.1% by mass of the plasticized material in toys and childcare articles which can be placed in the mouth of

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MANUFACTURER REQUEST FOR RISK EVALUATION

Classification:Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:Plasticizer DINP
MF:C26H42O4, C26H42O4
EINECS No.:249-079-5
Purity:99%
Type:PVC resin plasticizer
Usage:Coating Auxiliary Agents, Electronics Chemicals, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
MOQ:200kgs
Package:200kgs/battle
Shelf life:2 Years

Information relevant to the risk evaluation of DINP TSCA requires EPA to conduct risk evaluations to determine whether there is unreasonable risk to humans or the environment using the best

ACC’s High Phthalates Panel responds to EPA’s Draft Risk Evaluation for DIDP and Draft Hazard Assessments for DINP; group says the EPA did not find evidence to determine that DIDP causes cancer EPA’s conclusions are in line with those made by other regulatory agencies including that the weight of scientific evidence supports a

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Can EPA conduct a risk evaluation of DIDP & DINP?
The risk evaluations of DIDP and DINP are the first two manufacturer-requested risk evaluations EPA has conducted. Under TSCA, manufacturers can request that EPA conduct risk evaluations on chemicals they manufacture. EPA received and granted manufacturer requests for risk evaluations of DIDP and DINP in 2019. DIDP
Did ECHA re-evaluate DINP & DIDP?
When ECHA initiated its in-depth re-evaluation of DINP and DIDP in 2010 there was a general consensus that the liver carcinogenicity seen in rodents in response to exposure to DEHP, DINP and DIDP was of little or unclear relevance to humans. Therefore, ECHA’s draft review report of 7 May 2012 (ECHA 2012) did not review carcinogenicity in detail.
Are DIDP and DINP TSCA safe?
There are other uses of DIDP and DINP that are generally excluded from TSCA, such as personal care products, cosmetics, and food contact materials, and EPA did not evaluate risk associated with these uses. The risk evaluations of DIDP and DINP are the first two manufacturer-requested risk evaluations EPA has conducted.
What is a low concentration of DIDP and DINP?
The data shown in the table represent those samples where the concentration of DIDP and DINP was above 1%. Low concentrations of DIDP (typically below 1%) are indicated for many samples with concentrations of DINP in the range of 30-50%.
Is harmonised classification required for DINP & DIDP?
4.3.1 Classification and labelling in Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation) There is no harmonised classification for DINP and DIDP according to Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation). The EU Risk Assessments for DINP and DIDP (EC 2003a,b) had concluded that no classification was required for any endpoint.
What is a normal dose of DIDP compared to DINP?
It is apparent from Table 4.85 that most studies have reported medianadult exposure to DINP of around 1 µg/kg bw/daywith 95thpercentileintakes being generally less than 10 µg/kg/day. There is very few biomonitoring data for DIDP. Exposures to DIDP would appear to be smaller than for DINP.