Human Exposure to Diisononyl Phthalate (DINP) Brazil

Human Biological Monitoring of Diisononyl Phthalate

Classification:Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:DINP
MF:C26H42O4
EINECS No.:249-079-5
Purity:99.6%
Type:Adsorbent
Usage:Plastic Auxiliary Agents
MOQ:1000KG
Package:25kg/drum
Model Number:DINP

High molecular-weight phthalates, such as diisononyl phthalate (DINP), and diisodecyl phthalate (DIDP), are widely used as plasticizers in the manufacturing of polymers and consumer products. Human biological monitoring studies have employed the metabolites of

Mar 27, 2006Diisononyl phthalate (DINP) is a complex mixture of predominantly nine-carbon branched-chain dialkyl phthalate isomers. Similar to di(2-ethylhexyl) phthalate, a widely used phthalate, DINP causes antiandrogenic effects on

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Subacute exposure to di-isononyl phthalate alters the

Classification:Chemical Auxiliary Agent
CAS No.:28553-12-0
Other Names:Plasticizer DINP
MF:C26H42O4, C26H42O4
EINECS No.:271-090-9
Purity:99.9%
Type:plasticizer
Usage:Plastic Auxiliary Agents, Plasiticizer
MOQ:1000KG
Package:25kg/drum
Package:200kg/drum

Di-isononyl phthalate (DiNP), a common plasticizer used in polyvinyl chloride products, exhibits endocrine-disrupting capabilities. It is also toxic to the brain, reproductive

HUMAN EXPOSURE TO DIISONONYL PHTHALATE (DINP) For . creatinine clearance (C), David (2000) used a value of 20 mg/kg/day for adults, taken from Tietz (1986). That source

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Phthalate exposure and metabolic effects: a systematic

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:28553-12-0
MF:C26H42O4 Diisononyl Phthalate
EINECS No.:271-090-9
Purity:99.5%, 99.5%
Type:plasticizer
Usage:Plastic Auxiliary Agents, Plasiticizer
MOQ:1000KG
Package:25kg/drum
Storage:Dry Place

This review focuses on studies of phthalate exposure and metabolic-related outcomes. The phthalates evaluated in this paper are: di(2-ethylhexyl) phthalate (DEHP), diisononyl phthalate

exposure to DINP than is MNP (Koch et al. 2007; Silva et al. 2006b). Similarly, although only limited DIDP human exposure assess ment data exist to date (Silva et al. 2007a), based on

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Diisononyl Phthalate: Chemistry, Environmental Path,

Classification:Chemical Auxiliary Agent
CAS No.:68515-48-0
Other Names:DINP
MF:C26H42O4 Diisononyl Phthalate
EINECS No.:249-079-5
Purity:99.6%
Type:Plasiticizer
Usage:Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents
MOQ:200kgs
Package:200kgs/battle
Function:PVC Plasticizer

diisononyl phthalate (DINP) is currently manufactured as an isomeric mixture of di (C g to CIO)-orthophthalates, predominantly C 9, with a molecular weight in ISynonyms are isononyl

Human exposure to DINP may occur via oral, dermal, and inhalation exposure routes. Based upon the physiochemical characteristics of DINP and limited monitoring data, general

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Human Biological Monitoring of Diisononyl Phthalate

Classification:Chemical Auxiliary Agent
CAS No.:28553-12-0
Other Names:Di-isononyl phthalate
MF:C26H42O4, C26H42O4
EINECS No.:271-090-9
Purity:99%, 99%
Type:plasticizer
Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Petroleum Additives, Plastic Auxiliary Agents, Rubber Auxiliary Agents, Surfactants, Textile Auxiliary Agents, Water Treatment Chemicals
MOQ:200kgs
Package:200kgs/battle
Package:200kg/drum

Babich MA. The Risk of Chronic Toxicity Associated with Exposure to Diisononyl Phthalate (DINP) in Children's Products. Bethesda, Md, USA: United States Consumer Product Safety

However, exposure to DINP has been associated with anti-androgenic potential in male offspring and adults and decreased thyroid hormones in mother–child pairs. In conclusion, existing literatures

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Is the prevalence of human exposure to diisononyl phthalate (DINP) underestimated?
The use of MINP as the sole biomarker for human exposure to diisononyl phthalate (DINP) is an underestimation. DINP is a complex mixture of branched-chain dialkyl phthalate isomers, predominantly containing nine carbons in the alkyl chain. Therefore, we concluded that the prevalence of human exposure to DINP is underestimated.
What is diisononyl phthalate (DINP)?
Diisononyl phthalate (DINP) is a complex mixture of predominantly nine-carbon branched-chain dialkyl phthalate isomers. It is analyzed as a metabolite in human urine (J Chromatogr B 805:161-167).
How does Di-isononyl phthalate affect the gastrointestinal tract?
Di-isononyl phthalate (DiNP), a common plasticizer used in polyvinyl chloride products, exhibits endocrine-disrupting capabilities. It is also toxic to the brain, reproductive system, liver, and kidney. However, little is known about how DiNP impacts the gastrointestinal tract (GIT).
Does Di-isononyl phthalate affect morphology and endocrine function?
Chiu, K., Bashir, S.T., Nowak, R.A. et al. Subacute exposure to di-isononyl phthalate alters the morphology, endocrine function, and immune system in the colon of adult female mice.
Are DINP phthalates dangerous?
Recently, DINP and other related phthalates have received publicity as potential environmental contaminants and raised concern for human health. There are few restrictions on these substances regarding acceptable levels in industrial wastes, liquid effluents, or workplace environments.
Does diisononyl phthalate cause hepatic and renal tissue injury?
Ma, P. et al. Oral exposure of Kunming mice to diisononyl phthalate induces hepatic and renal tissue injury through the accumulation of ROS. Protective effect of melatonin. Food Chem. Toxicol. 68, 247–256 (2014). Byers, S. L. et al. Mouse estrous cycle identification tool and images. PLoS ONE 7 (4), e35538 (2012).