The action of plasticizer dinch Vietnam

  • The action of plasticizer dinch Vietnam
  • The action of plasticizer dinch Vietnam
  • The action of plasticizer dinch Vietnam

The Emerging Plasticizer Alternative DINCH and Its

  • Classification:Chemical Auxiliary Agent
  • CAS No.:166412-78-8
  • Other Names:DINCH
  • MF:C26H48O4
  • EINECS No.:431-890-2
  • Purity:0.98
  • Usage:Plastic Auxiliary Agents, Rubber Auxiliary Agents
  • MOQ:1000KG
  • Package:25kg/drum
  • Color:colorless

Keywords: DINCH, plasticizer, macrophage, proteomics, immunotoxicity. 1. Introduction. As part of the innate immune system, macrophages are found in most organs and tissues of the body . Proposed mode of action of DINCH and MINCH in THP-1 macrophages. ROS levels were

Along with the restrictions of phthalate esters (PAEs), a variety of nonphthalate plasticizers (NPPs) have been increasingly used for industrial needs. Knowledge remains limited on the environmental occurrences, fate,

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The Emerging Plasticizer Alternative DINCH

  • Classification:Chemical Auxiliary Agent
  • CAS No.:166412-78-8
  • Other Names:DINCH
  • MF:C26H48O4
  • EINECS No.:431-890-2
  • Purity:0.98
  • Usage:Plastic Auxiliary Agents, Rubber Auxiliary Agents
  • MOQ:200kgs
  • Package:200kgs/battle
  • Color:colorless

Proposed mode of action of DINCH and MINCH in THP-1 macrophages. ROS levels were increased, leading to activation of NF-κB and subsequent release of TNF and IL1-β, thereby inducing a pro

Hexamoll® DINCH® (diisononyl-cyclohexane-1,2-dicarboxylate) is a new high-molecular-weight plasticizer and a phthalate substitute. In this study, the metabolism of DINCH® was investigated by

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Uses and occurrences of five major alternative

  • Classification:Chemical Auxiliary Agent
  • CAS No.:166412-78-8
  • Other Names:Plasticizer
  • MF:C26H48O4
  • EINECS No.:431-890-2
  • Purity:99.50%, 99.50%
  • Usage:Coating Auxiliary Agents, Leather Auxiliary Agents, Paper Chemicals, Plastic Auxiliary Agents, Rubber Auxiliary Agents
  • MOQ:1000KG
  • Package:25kg/drum
  • Feature:High Efficiency

Background and purpose . Non-phthalate plasticizers are being increasingly used in commercial and consumer products, to replace phthalates. Among major non-phthalate plasticizer groups, we chose five alternative

SGBS preadipocytes were continuously exposed to 10 nM and 10 µM of the plasticizers DINCH, DINP, and DPHP or their metabolites MINCH, MHINP, OH-MPHP for up

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Alternative Plasticizers As Emerging Global

  • Classification:Chemical Auxiliary Agent
  • CAS No.:166412-78-8
  • Other Names:Plasticizer
  • MF:C26H48O4
  • EINECS No.:431-890-2
  • Purity:99%, ≥99.0%
  • Usage:Plastic Auxiliary Agents
  • MOQ:1000KG
  • Package:25kg/drum
  • Application:plasticizer

The most abundant plasticizers in preschool dust were the phthalates di-isononyl phthalate (DiNP) and di-(2-ethylhexyl) phthalate (DEHP) with geometric mean levels of 450 and 266 μg/g dust, resp., and the non

DINCH and MINCH induced cellular stress and pro-inflammatory effects in macrophages, which may lead to adverse health effects, and were associated with oxidative stress, mitochondrial

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The Emerging Plasticizer Alternative DINCH and Its

  • Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
  • CAS No.:166412-78-8
  • Other Names:DINCH
  • MF:C26H48O4
  • EINECS No.:431-890-2
  • Purity:99.5%
  • Usage:Plastic Auxiliary Agents
  • MOQ:1000KG
  • Package:25kg/drum
  • Type:Adsorbent

Human THP-1 macrophages were exposed to 10 nM-10 μM DINCH or MINCH for 4 h, 16 h, and 24 h. To decipher the underlying mechanism of action, we applied an untargeted

Plasticizers are known to impact different steps of TH signaling. For instance, they can bind to THRs, retinoid X receptor (RXR), thyroid stimulating hormone receptor (TSHr), thyroglobulin (TG).

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  • Which plasticizers have the highest adipogenic potential?
  • Among several compounds that showed interaction with PPARγ, the metabolites MINCH, MHINP, and OH-MPHP of the plasticizers DINCH, DINP, and DPHP exerted the highest adipogenic potential in human adipocytes.
  • Do plasticizers cause adipogenesis and PPAR interaction?
  • 20 plasticizers and their metabolites were screened for PPARγ interaction. Metabolites of DINCH, DINP, and DPHP most potently induced human adipogenesis. These metabolites enhanced adipogenesis and PPARγ markers similar to rosiglitazone. Both compound groups caused oxidative stress and dysfunction in mature adipocytes.
  • Are there alternative plasticizers?
  • There are a considerable number of alternative plasticizers in employment, without any toxicological data available (dibutyl adipate, diethylene glycol dibenzoate, and bis-2-ethylhexyl sebacate, to name a few).
  • How many chemicals can be used as plasticizers?
  • There are about 30 000 chemicals can potentially be utilized as plasticizers. (1) Phthalate plasticizers are a commonly utilized compound, comprising up to 85% of the total plasticizers in the market.
  • Is food intake an important exposure pathway for plasticizers?
  • In addition, ATBC and GMO have been reported to be directly used in the food industry as food additives. (48−52) Thus, food intake could represent an important exposure pathway for selected plasticizers.
  • Are plasticizers triggering adipogenesis in human preadipocytes?
  • In summary, several plasticizers and their metabolites were able to bind to PPARγ, to activate it, and to increase lipid accumulation, and thus, potentially are triggering adipogenesis in human preadipocytes. Nevertheless, there are disparities between binding, activation, and induction of lipid accumulation in some cases. 3.2.

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