Toxicity and molecular effects of di-n-butyl phthalate (DBP) on CYP1A Pakistan

Toxicity and molecular effects of di-n-butyl phthalate

Classification:Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:DBP
MF:C16H2204
EINECS No.:201-557-4
Purity:≥99.5
Type:Adsorbent
Usage: Paper Chemicals, Leather Auxiliary Agents,
MOQ:25kg/bag
Package:200kg/drum
Sample:Availabe

Phthalate esters are used in the plastic industry as plasti-cizers and solvents, i.e., in varnishes, perfumes, cos-metics, children’s toys for increasing the flexibility and workability of high

The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of di-n-butyl phthalate. It contains

Online Inquiry

Toxicity and molecular effects of di-n-butyl phthalate (DBP)

Classification:Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Bis(2-ethylhexyl) phthalate, Ethyl..
MF:C16H22O4
EINECS No.:201-557-4
Purity:99%, 99%
Type:Plasticizer, Plasticizer DBP Dibutyl Phthalate
Usage: Electronics Chemicals, Plastic Auxiliary Agents
MOQ:25kg/bag
Package:200kg/drum
Sample:Availabe

Evaluating the tissue-specific alterations of CYP1A, SOD, and GPx levels can be used as specific and effective biomarkers for ecotoxicological monitoring of DBP pollution and

To study the toxic effects of phthalate esters on the aquatic creatures, carps were exposed to dibutyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP) of six different

Online Inquiry

Toxicity Review for Di-n-butyl Phthalate (Dibutyl

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:liquid dbp
MF:C16H2204
EINECS No.:201-557-4
Purity:99.5%
Type:Chemical auxiliary agent, Plasticizer
Usage: Surfactants, Textile Auxiliary Agents,
MOQ:200kgs
Package:200kgs/battle
Quality control:COA ,SDS,TDS

metabolite is also considered one of the major metabolites for another phthalate, benzyl butyl phthalate (Ema, 1995). DBP’s potential risk to human health has been, and continues to be,

Sep 1, 2001The ATSDR toxicological profile succinctly characterizes the toxicology and adverse health effects information for the toxic substance described therein. Each peer-reviewed profile

Online Inquiry

PUBLIC HEALTH STATEMENT Toxicological

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Elasticizer
MF:C16H2204
EINECS No.:201-557-4
Purity:99.5%, 99.5%min
Type:plasticizer
Usage: Leather Auxiliary Agents, Paper Chemicals,
MOQ:200kgs
Package:200kgs/battle
Application:Plasticizer

1.1. WHAT IS DI-n-BUTYL PHTHALATE?Di-n-butyl phthalate is an odorless and colorless or faintly yellow oily liquid that does not occur in nature.It is a chemical that is added to hard plastics to make them soft. The plastics that di-n-butyl

Di-n-butyl phthalate (DBP), a widely used plasticizer in the plastic industry, affects regulation of the endocrine system and causes toxicity in animals. In the present study, we

Online Inquiry

Toxicity and molecular effects of di-n-butyl phthalate (DBP)

Classification:Chemical Auxiliary Agent, Chemical Auxiliary Agent
CAS No.:84-74-2
Other Names:Bis(2-ethylhexyl) phthalate, Ethyl..
MF:C16H2204
EINECS No.:201-557-4
Purity:99.5%Min
Type:Plasticizer, Plasticizer DBP Dibutyl Phthalate
Usage: Rubber Auxiliary AgentsPlastic Auxiliary Agents,
MOQ:200kgs
Package:200kgs/battle
Delivery:Within 7-15 Days

Toxicity and molecular effects of di-n-butyl phthalate (DBP) on CYP1A, SOD, and GPx in Cyprinus carpio (common carp) Agus, Hizlan H.; Sümer, Sibel; Erkoç, Figen; Abstract.

Toxicity and molecular effects of di-n-butyl phthalate (DBP) on CYP1A, SOD, and GPx in Cyprinus carpio (common carp) Agus, Hizlan H.; Sümer, Sibel; Erkoç, Figen; Abstract. Publication: Environmental Monitoring and Assessment. Pub Date: July 2015 DOI: 10.1007/s10661-015-4622-3 Bibcode:

Online Inquiry

Why is di n -butyl phthalate toxic?
A susceptible population will exhibit a different or enhanced response to di- n -butyl phthalate than will most persons exposed to the same level of di- n -butyl phthalate in the environment. Reasons may include genetic makeup, age, health and nutritional status, and exposure to other toxic substances (e.g., cigarette smoke).
Does di n -butyl phthalate cause respiratory effects?
Information on the potential of di- n -butyl phthalate to induce respiratory effects is limited to a study by Kawano (1980a), which found an increase in relative lung weight in rats exposed to 50 mg/m 3 di- n -butyl phthalate 6 hours/day for 6 months ( Kawano 1980a ); lung weight was not altered in the 0.5 mg/m 3 group.
How dangerous is di-n-butyl phthalate?
Di- n -butyl phthalate has low acute toxicity in animals. Single doses of 8,000 mg/kg killed four of nine rats in one study ( Smith 1953 ), but other studies indicate the acute oral LD 50 in rats and mice is in excess of 20,000 mg/kg ( Hardin et al. 1987; White et al. 1983 ).
Does di-n-butyl phthalate cause hypertension?
Hypertension was reported in workers exposed to di- n -butyl phthalate for 0.5–19 years at concentrations of 1.7–66 mg/m 3; the frequency increased with length of employment ( Milkov et al. 1973 ). These workers were also exposed to other plasticizers, so the effects seen may not have been caused by di- n -butyl phthalate exposure.
Does di-n-butyl phthalate affect body weight?
Body Weight Effects. Several studies have evaluated the effect of oral exposure of animals to di- n -butyl phthalate on body weight ( BIBRA 1986; Gray et al. 1982; Lamb et al. 1987; Murakami et al. 1986, 1986b; Nikonorow et al. 1973; NTP 1984, 1995; Oishi and Hiraga 1980a; Smith 1953 ).
Does di-n-butyl phthalate affect the liver?
Systemic, reproductive, and developmental effects have been observed in animals following oral exposure. The liver appears to be the most sensitive systemic target in rats and mice exposed to di- n -butyl phthalate in the diet for 13 weeks ( NTP 1995; Schilling et al. 1992 ).